Compile Data Set for Download or QSAR
maximum 50k data
Found 130 of affinity data for UniProtKB/TrEMBL: Q5JUK3
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557676(CHEMBL4763955)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557672(CHEMBL4788669)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50:  40nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557678(CHEMBL4754084)
Affinity DataIC50:  61nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557660(CHEMBL4783741)
Affinity DataIC50:  136nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557666(CHEMBL4786255)
Affinity DataIC50:  165nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557652(CHEMBL4793291)
Affinity DataIC50:  167nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557679(CHEMBL4793279)
Affinity DataIC50:  195nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557677(CHEMBL4750925)
Affinity DataIC50:  322nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557656(CHEMBL4783466)
Affinity DataIC50:  335nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557674(CHEMBL4795194)
Affinity DataIC50:  454nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557675(CHEMBL4743249)
Affinity DataIC50:  505nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557673(CHEMBL4781553)
Affinity DataIC50:  573nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557682(CHEMBL4745211)
Affinity DataIC50:  744nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557683(CHEMBL4758890)
Affinity DataIC50:  778nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557659(CHEMBL4779088)
Affinity DataIC50:  977nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617416(US20230285377, Example 5)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617461(US20230285377, Example 45)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617460(US20230285377, Example 44)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617455(US20230285377, Example 39)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617452(US20230285377, Example 36)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617451(US20230285377, Example 35)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617448(US20230285377, Example 32)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617447(US20230285377, Example 31)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617439(US20230285377, Example 25)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617412(US20230285377, Example 1)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617413(US20230285377, Example 2)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617415(US20230285377, Example 4)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617418(US20230285377, Example 6)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617419(US20230285377, Example 7)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617422(US20230285377, Example 10)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617423(US20230285377, Example 11)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617424(US20230285377, Example 12)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617425(US20230285377, Example 13)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617426(US20230285377, Example 14)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617428(US20230285377, Example 16)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617431(US20230285377, Example 19)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM617434(US20230285377, Example 21)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50607075(CHEMBL5220335)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557664(CHEMBL4750826)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50607067(CHEMBL5218475)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557670(CHEMBL4744857)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557658(CHEMBL4789512)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50607064(CHEMBL1730394)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of wild-type Slack (unknown origin) expressed in HEK293 cells measured by whole-cell electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50607085(CHEMBL5221076)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of wild-type Slack (unknown origin) expressed in HEK293 cells measured by whole-cell electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557685(CHEMBL4750807)
Affinity DataIC50:  1.88E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50607079(CHEMBL5219802)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of wild-type Slack (unknown origin) expressed in HEK293 cells measured by whole-cell electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50607076(CHEMBL5219391)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50607069(CHEMBL5220721)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of wild-type Slack (unknown origin) expressed in HEK293 cells measured by whole-cell electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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